Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759799 | Biochemical and Biophysical Research Communications | 2013 | 4 Pages |
Abstract
⺠α-Iso-cubebenol stimulated cellular calcium increase in human neutrophils. ⺠α-Iso-cubebenol enhanced degranulation activity in neutrophils. ⺠α-Iso-cubebenol stimulated neutrophil chemotactic migration via CXCR2. ⺠α-Iso-cubebenol showed anti-septic activity via CXCR2. ⺠The finding suggests α-iso-cubebenol and CXCR2 as therapeutic approach to treat sepsis.
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Authors
Young Su Jung, Sung Kyun Lee, Chang Youp Ok, Eun Jung Cho, Joon Seong Park, Young Whan Choi, Yoe-Sik Bae,