| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759805 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠The Chk1 activation domain (CAD) of TopBP1 is critical in DNA damage response. ⺠WD40-repeat protein WDR18 associates with TopBP1 in vitro and in vivo. ⺠WDR18 and TopBP1 association is required for AT70-induced Chk1 phosphorylation. ⺠WDR18 is required for AT70-triggered Chk1 phosphorylation. ⺠WDR18 associates with Chk1 in vitro.
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Authors
Shan Yan, Jeremy Willis,