Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759807 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠IL-1β, ROS and IL-8 increased correlating to HIF-1α by hypoxia in human chondrocytes. ⺠IL-8 responsive to IL-1β was potentiated by hypoxia in human chondrocytes. ⺠Hypoxia may make cartilages prone to initiate inflammation and catabolism. ⺠Hypoxia per se can be a natural predisposing condition for cartilage degeneration.
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Authors
Young Hoon Hong, Chan Won Park, Hee Sun Kim, Kyu Chang Won, Yong Woon Kim, Choong Ki Lee,