Article ID Journal Published Year Pages File Type
10759807 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► IL-1β, ROS and IL-8 increased correlating to HIF-1α by hypoxia in human chondrocytes. ► IL-8 responsive to IL-1β was potentiated by hypoxia in human chondrocytes. ► Hypoxia may make cartilages prone to initiate inflammation and catabolism. ► Hypoxia per se can be a natural predisposing condition for cartilage degeneration.
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