| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759812 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠Berberine inhibits proinflammatory response to LPS in macrophage by HO-1. ⺠It is the first report that berberine inhibits HMGB1 releases in activated macrophage. ⺠Berberine increases the HO-1 level through p38 MAPK and Nrf2 in activated macrophage. ⺠Berberine may be useful as a therapeutic agent for treatment of inflammatory diseases.
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Authors
Danbi Lee, Jinbum Bae, Yoon Kyu Kim, Minchan Gil, Joo-Yong Lee, Chan-Sik Park, Kyung Jin Lee,