Article ID Journal Published Year Pages File Type
10759823 Biochemical and Biophysical Research Communications 2013 7 Pages PDF
Abstract
► Sulfuretin enhances the expression of miR-30C, leading cells to apoptosis and cell cycle arrest. ► miR-30C selectively downregulates cyclin D1 and D2 but not D3. ► miR-30C mediates the tumor suppressive effects of sulfuretin in PC-3. ► Target validation analysis revealed Cyclin D1 and D2 as targets of miR-30C. ► New insights on sulfuretin as a potential anticancer drug.
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