| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759824 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
⺠We hypothesize that neurodegeneration in anti-NGF is due to NGF/proNGF imbalance. ⺠We propose that the proNGF co- receptor sortilin contributes to the neurodegeneration. ⺠We analyzed anti-NGF mice crossed to sortilin knockout mice. ⺠Sortilin loss partially protected AD10 anti-NGF mice from neurodegeneration.
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Authors
Simona Capsoni, Gianluca Amato, Domenico Vignone, Chiara Criscuolo, Anders Nykjaer, Antonino Cattaneo,