| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759827 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
⺠A cDNA encoding a P450 (CYP82N4) involved in sanguinarine biosynthesis was isolated from Papaver somniferum (opium poppy). ⺠Expression of the corresponding gene was detected in opium poppy roots and elicitor-treated cell suspension cultures. ⺠The CYP82N4 cDNA was expressed in Saccharomyces cerevisiae. ⺠Recombinant CYP82N4 converted N-methylated protoberberines to protopine alkaloids.
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Authors
Guillaume A.W. Beaudoin, Peter J. Facchini,