Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759830 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠Gene set enrichment analysis indicated mir-30d might regulate the autophagy pathway. ⺠mir-30d represses the expression of BECN1, BNIP3L, ATG12, ATG5 and ATG2. ⺠BECN1, BNIP3L, ATG12, ATG5 and ATG2 are direct targets of mir-30d. ⺠mir-30d inhibits autophagosome formation and LC3B-I conversion to LC3B-II. ⺠mir-30d regulates the autophagy process.
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Authors
Xiaojun Yang, Xiaomin Zhong, Janos L. Tanyi, Jianfeng Shen, Congjian Xu, Peng Gao, Tim M. Zheng, Angela DeMichele, Lin Zhang,