Article ID Journal Published Year Pages File Type
10759883 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► TGF-β1 transcriptionally increases expression of the Angptl2 gene. ► We identified specific Smad Binding Element (SBE) within Angptl2 promoter. ► TGF-β1-mediated induction of Angptl2 gene requires Smad3. ► This is the first report about a connection between TGF-β signaling and Angptl2 gene.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Angiopoietin-like protein 2, a chronic inflammatory mediator, is a new target induced by TGF-β1 through a Smad3-dependent mechanism
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