Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759888 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠We show that the role of progalanin activation in extracellular component. ⺠MMP activities and angiogenesis were increased by treatment of galanin or progalanin. ⺠Plasmin inhibitor diminished MMP activities and angiogenesis of progalanin. ⺠Extracellular processing of progalanin is a novel mechanism for tumor growth.
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Authors
Hiroyuki Yamamoto, Rina Okada, Kazuaki Iguchi, Satoshi Ohno, Takashi Yokogawa, Kazuya Nishikawa, Keiko Unno, Minoru Hoshino, Atsushi Takeda,