Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759896 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠Conserved hydrogen bond and water among MDR HIV-1 protease substrate complexes. ⺠Hydrogen bonds, waters crucial in substrate recognition, protease stabilization. ⺠Flap-ligand bridging water is missing in MDR HIV-1 protease substrate complexes.
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Authors
Zhigang Liu, Yong Wang, Ravikiran S. Yedidi, Tamaria G. Dewdney, Samuel J. Reiter, Joseph S. Brunzelle, Iulia A. Kovari, Ladislau C. Kovari,