| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759907 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠CanPIs structure is predominantly β-sheet and unordered. ⺠CanPI-7 also reveals signature of polyproline fold in CD spectra. ⺠Inhibition kinetics reveals higher potency of multidomain CanPIs against proteases. ⺠CanPIs highly stabile under extreme pH, temperature and denaturing conditions. ⺠Structure prediction, MALDI-TOF-MS and docking reveal binding mechanism of multidomain CanPI-7.
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Authors
Manasi Mishra, Rakesh S. Joshi, Sushama Gaikwad, Vidya S. Gupta, Ashok P. Giri,