| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759920 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠A Ca2+ channel was identified in the plasma membrane of Leishmania mexicana. ⺠The channel has features similar to the human L-type voltage-gated Ca2+ channel. ⺠Ca2+ entry is blocked by verapamil, nifedipine and diltiazem. ⺠Bay K 8644, a VGCC agonist, opened this trypanosomatid channel. ⺠Different to its human counterpart, sphingosine was able to open this channel.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Gustavo Benaim, Yael GarcÃa-Marchán, Claudia Reyes, Graciela Uzcanga, Katherine Figarella,