Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759985 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Autophagosomes were equally increased in both p53-deficient and -proficient differentiated and hypertrophic adipocytes. ⺠Autophagic flux was decreased in the differentiated and hypertrophic adipocytes. ⺠In differentiated and hypertrophic adipocytes autophagosomes accumulate in a p53-independent manner and the reduced autophagic flux causes their accumulation.
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Authors
Kentaro Mikami, Naoyuki Okita, Yuki Tokunaga, Tomoyo Ichikawa, Tatsuya Okazaki, Kanako Takemoto, Wataru Nagai, Shingo Matsushima, Yoshikazu Higami,