Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760034 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
⺠We examined the anti-athrogenic effect of apocynin in atherosclerotic model mice. ⺠Apocynin prevented atherosclerotic lesion formation. ⺠Apocynin suppressed ROS production in aorta and in macrophages. ⺠Apocynin suppressed cytokine expression and cell proliferation in macrophages. ⺠Apocynin may be beneficial compound for the prevention of atherosclerosis.
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Authors
Hiroyuki Kinoshita, Takeshi Matsumura, Norio Ishii, Kazuki Fukuda, Takafumi Senokuchi, Hiroyuki Motoshima, Tatsuya Kondo, Kayo Taketa, Shuji Kawasaki, Satoko Hanatani, Motohiro Takeya, Takeshi Nishikawa, Eiichi Araki,