| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760037 | Biochemical and Biophysical Research Communications | 2013 | 5 Pages |
Abstract
⺠First time to show the reduced KLF2 level in AD transgenic mice. ⺠First time to show Aβ1-42 disrupts the expression of KLF2. ⺠Overexpression of KLF2 rescued impaired expression of Occludin induced by Aβ. ⺠p53 mediated impaired expression and function of KLF2 induced by Aβ. ⺠Suggesting the role of KLF2 in impaired brain blood barrier in AD.
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Authors
Chunyan Wu, Fengling Li, Guosheng Han, Zhihui Liu,