Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760050 | Biochemical and Biophysical Research Communications | 2013 | 5 Pages |
Abstract
⺠Bc-SMase binds to ganglioside GM3. ⺠The β-hairpin of Bc-SMase plays an important role in binding to GM3. ⺠Trp284 and Phe285 at the β-hairpin are essential for the binding to GM3. ⺠Bc-SMase requires a sialic acid of gangliosides for membrane binding.
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Authors
Masataka Oda, Aoi Fujita, Kensuke Okui, Kazuaki Miyamoto, Masahiro Shibutani, Teruhisa Takagishi, Masahiro Nagahama,