Article ID Journal Published Year Pages File Type
10760055 Biochemical and Biophysical Research Communications 2013 7 Pages PDF
Abstract
► Fe-SOD selectively targeted cancer cells independent of p53 status. ► Co-treatment of Fe-SOD and Nutlin3 showed synergistic inhibition on cancer cells in vitro. ► p27 was synergistically induced by Fe-SOD and p53. ► Co-treatment of Fe-SOD and Nutlin3 further exhibited synergistic inhibition on tumor growth in vivo.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Fe-SOD cooperates with Nutlin3 to selectively inhibit cancer cells in vitro and in vivo
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