| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760110 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
⺠Anti-histone H1 autoantibody (anti-H1) acts on T cells to inhibit their activation. ⺠Anti-H1 suppresses T cell activation in Treg cell-dependent and -independent manners. ⺠Suboptimal dose of anti-H1 enhances suppressor function of Treg cells. ⺠High dose of anti-H1 directly inhibits T cell receptor signaling.
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Authors
Yuki Takaoka, Seiji Kawamoto, Akiko Katayama, Toshiaki Nakano, Yasushi Yamanaka, Miki Takahashi, Yayoi Shimada, Kuei-Chen Chiang, Naoya Ohmori, Tsunehiro Aki, Takeshi Goto, Shuji Sato, Shigeru Goto, Chao-Long Chen, Kazuhisa Ono,