Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760155 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠We inserted multiple platelet factor 4-driven human FVIII genes into a HAC vector. ⺠We generated an integration-free hemophilia mouse-derived iPS cells. ⺠We confirmed the iPS cell-mediated FVIII expression in megakaryocytes/platelets.
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Authors
Yuwna Yakura, Chie Ishihara, Hajime Kurosaki, Yasuhiro Kazuki, Norio Komatsu, Yoshiaki Okada, Takefumi Doi, Hiroyuki Takeya, Mitsuo Oshimura,