Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760168 | Biochemical and Biophysical Research Communications | 2013 | 5 Pages |
Abstract
⺠Overexpression of HIC1 reduces p21 expression. ⺠Knock-down of HIC1 superinduces p21 in response to DNA damages independently of p53. ⺠HIC1 binds to the p21 promoter to repress its transcription. ⺠HIC1 is a key player of the DNA damage response.
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Authors
Vanessa Dehennaut, Ingrid Loison, Gaylor Boulay, Capucine Van Rechem, Dominique Leprince,