Article ID Journal Published Year Pages File Type
10760168 Biochemical and Biophysical Research Communications 2013 5 Pages PDF
Abstract
► Overexpression of HIC1 reduces p21 expression. ► Knock-down of HIC1 superinduces p21 in response to DNA damages independently of p53. ► HIC1 binds to the p21 promoter to repress its transcription. ► HIC1 is a key player of the DNA damage response.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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