Article ID Journal Published Year Pages File Type
10760174 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► Infusion of BAIB increased dimethylarginine plasma levels in mice. ► Infusion of BAIB decreased plasma levels of AGXT2-derived ADMA metabolites. ► Expression of Agxt2 was not affected by BAIB infusion. ► First in vivo evidence that endogenous Agxt2 regulates ADMA and SDMA plasma levels. ► Heritable hyper-BAIB-uria may be associated with impaired methylarginine metabolism.
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