| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760201 | Biochemical and Biophysical Research Communications | 2013 | 4 Pages |
Abstract
⺠Molecular models of T2R4 built using rhodopsin crystal structure as template. ⺠Chimeric T2R4s with the rhodopsin N-terminal 33 and 38 amino acids characterized. ⺠Rho33-T2R4 chimera showed 2.5-fold increase in functional expression of T2R4. ⺠Rho33-T2R4 does not cause perturbations in T2R4 structure. ⺠Rho38-T2R4 causes extension of the transmembrane helix I in T2R4.
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Authors
Sai Prasad Pydi, Raja Chakraborty, Rajinder Pal Bhullar, Prashen Chelikani,