Article ID Journal Published Year Pages File Type
10760217 Biochemical and Biophysical Research Communications 2013 5 Pages PDF
Abstract
► EGCG down-regulated UHRF1 and DNMT1 expressions in jurkat cells. ► Down-regulation of UHRF1 enhanced expression of p16INK4A and p73. ► UHRF1 over-expression counteracted EGCG-induced apoptosis and G1 arrested cells. ► Mutants of the SRA domain of UHRF1 were unable to down-regulate p16INK4A and p73.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , , , , , , , ,