Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760217 | Biochemical and Biophysical Research Communications | 2013 | 5 Pages |
Abstract
⺠EGCG down-regulated UHRF1 and DNMT1 expressions in jurkat cells. ⺠Down-regulation of UHRF1 enhanced expression of p16INK4A and p73. ⺠UHRF1 over-expression counteracted EGCG-induced apoptosis and G1 arrested cells. ⺠Mutants of the SRA domain of UHRF1 were unable to down-regulate p16INK4A and p73.
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Authors
Mayada Achour, Marc Mousli, Mahmoud Alhosin, Abdulkhaleg Ibrahim, Jean Peluso, Christian D. Muller, Valérie B. Schini-Kerth, Ali Hamiche, Sirano Dhe-Paganon, Christian Bronner,