Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760221 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠Omega-3 PUFA has a direct anti-oxidant effect in adipocytes. ⺠EPA and DHA induce HO-1 expression in 3T3-L1 adipocytes. ⺠Omega-3 PUFA and its end-product, 4-HHE, activates the Nrf-2/HO-1 pathway. ⺠Omega-3 PUFA protects against oxidative stress-induced cytotoxicity.
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Authors
Chisato Kusunoki, Liu Yang, Takeshi Yoshizaki, Fumiyuki Nakagawa, Atsushi Ishikado, Motoyuki Kondo, Katsutaro Morino, Osamu Sekine, Satoshi Ugi, Yoshihiko Nishio, Atsunori Kashiwagi, Hiroshi Maegawa,