Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760246 | Biochemical and Biophysical Research Communications | 2013 | 5 Pages |
Abstract
⺠Degradation of p21 proteins is required for UV-induced AR-mediated apoptosis. ⺠AR down-regulates basal p21 expression in a transcription independent manner. ⺠AR controls basal p21 expression through the PIRH2-p53-p21 axis. ⺠Down-regulation of basal p21 expression by AR reduces cell death threshold.
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Authors
Yuting Lin, Ziyan Lu, John Kokontis, Jialing Xiang,