Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760265 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠The IL-35 subunits were found to be expressed concurrently in human cancer cells. ⺠TNF-α and IFN-γ stimulation increased IL-35 expression in human cancer cells. ⺠IL-35 over-expression suppressed human cancer cell growth via cell cycle arrest. ⺠IL-35 over-expression increased the apoptosis sensitivity of human cancer cells. ⺠IL-35 regulated the expression of genes related to cell cycle and apoptosis.
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Authors
Jun Long, Xulong Zhang, Mingjie Wen, Qingli Kong, Zhe Lv, Yunqing An, Xiao-Qing Wei,