| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760268 | Biochemical and Biophysical Research Communications | 2013 | 5 Pages |
Abstract
⺠Physiological levels of vitamin D can induce an increase in Mdm2 expression. ⺠Mdm2 and VDR levels are increased after vitamin D treatment. ⺠Mdm2-P2 initiated transcripts are increased with vitamin D treatment. ⺠A VDR binding site was detected on the Mdm2 promoter and was bound by VDR. ⺠Activation of Mdm2 by vitamin D requires the presence of wild type p53.
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Authors
Hankui Chen, Grant Reed, Janete Guardia, Sandeep Lakhan, Oliver Couture, Emily Hays, Nalini Chandar,