| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760270 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠Lipopolysaccharide (LPS) is a stimulator of osteoclastogenesis and bone loss. ⺠RAW264.7 cells exposed to LPS form osteoclast-like multinucleated cells. ⺠Activating liver X receptor inhibits osteoclasts and promotes macrophage formation. ⺠These cells are highly phagocytic so could be involved in maintaining healthy tissue. ⺠Thus the LXR is involved in the fate determination of myeloid progenitor cells.
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Authors
Kirsten M. Robertson Remen, Jan-Ã
ke Gustafsson, Göran Andersson,