| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760275 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠Protocatechualdehyde (PCA) suppressed cell proliferation and induced apoptosis in human colorectal cancer cells. ⺠PCA enhanced transcriptional downregulation of cyclin D1 gene. ⺠PCA suppressed HDAC2 expression and activity. ⺠These findings suggest that anti-cancer activity of PCA may be mediated by reducing HDAC2-derived cyclin D1 expression.
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Authors
Jin Boo Jeong, Seong-Ho Lee,