| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760279 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠ZNF131 directly interacts with ERα. ⺠The binding affinity of ZNF131 to ERα increases upon E2 stimulation. ⺠ZNF131 inhibits ERα-mediated trans-activation by suppressing its homo-dimerization. ⺠ZNF131 inhibits ERα-dimerization and E2-induced breast cancer cell proliferation. ⺠ZNF131 inhibits estrogen signaling by acting as an ERα-co-repressor.
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Authors
Yohan Oh, Kwang Chul Chung,