Article ID Journal Published Year Pages File Type
10760283 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► The p38 MAPK signaling pathway regulates cardiac remodeling. ► Human cardiac fibroblasts express the α, γ and δ subtypes of p38 MAPK. ► IL-1 selectively stimulates p38α and p38γ activation. ► p38α is important for IL-1-induced IL-6 and MMP-3 expression in cardiac fibroblasts.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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