Article ID Journal Published Year Pages File Type
10760305 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► 27OHChol or 7αOHChol induced transcription and intracellular expression of TNF-α in macrophages. ► Exposure of 27OHChol- or 7αOHChol-treated THP-1 macrophages to LPS resulted in augmentation in TNF-α production. ► TO-901317, pertussis toxin, PP2, and LY294002 attenuated expression of TNF-α induced by oxysterols.
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