Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760305 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠27OHChol or 7αOHChol induced transcription and intracellular expression of TNF-α in macrophages. ⺠Exposure of 27OHChol- or 7αOHChol-treated THP-1 macrophages to LPS resulted in augmentation in TNF-α production. ⺠TO-901317, pertussis toxin, PP2, and LY294002 attenuated expression of TNF-α induced by oxysterols.
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Authors
Sun-Mi Kim, Hyojung Jang, Yonghae Son, Sae-A. Lee, Sun-Sik Bae, Young Chul Park, Seong-Kug Eo, Koanhoi Kim,