| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760309 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠atRA decreases eNOS-Ser1179 phosphorylation and NO production in BAEC. ⺠atRA increases total cellular PP2A activity. ⺠atRA increases the levels of PP2A B56α protein and mRNA, but not those of PP2A Cα. ⺠PP2A B56α mediates atRA-induced decreases in eNOS-Ser1179 phosphorylation and NO production in BAEC.
Keywords
AMPKcalmodulin-dependent kinase IIBAECDAF-FMpKaCaMKIIeNOS3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideAMP-activated protein kinaseatRADMSOMTTsiRNAall-trans retinoic acidOkadaic acidsmall interference RNADimethyl sulfoxideendothelial cell(s)Bovine aortic endothelial cellsendothelial nitric oxide synthaseDephosphorylationNitric oxideProtein phosphataseprotein phosphatase 2Aprotein kinase A
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Jung-Hyun Park, Hye Youn Sung, Jee Young Lee, Hyun Jin Kim, Jung-Hyuck Ahn, Inho Jo,