| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760312 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠We studied expression of ILK, PINCH, parvin, Mig2 and Migfilin in osteoarthritis. ⺠We show that ILK and Migfilin were upregulated in osteoarthritic chondrocytes. ⺠We show for the first time that migfilin silencing exacerbates osteoarthritis. ⺠We provide a link between migfilin and β-catenin activation in OA chondrocytes. ⺠In osteoarthritic chondrocytes migfilin is inversely correlated with β-catenin.
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Authors
Vasiliki Gkretsi, Vassilis Papanikolaou, Stephanie Dubos, Ioanna Papathanasiou, Nikolina Giotopoulou, Vaia Valiakou, Chuanyue Wu, Konstantinos N. Malizos, Aspasia Tsezou,