Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760317 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
⺠IL-6 is a trophic molecule for axotomized retinal ganglion cell survival in vitro. ⺠A1 adenosine receptors mediate the effect of IL-6 on retinal ganglion cell survival. ⺠Neutralization of BDNF inhibited the trophic effect of IL-6 on axotomized retinal ganglion cell. ⺠BDNF plays a role in the trophic effect of IL-6 on axotomized retinal ganglion cells.
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Authors
Rafael PerÃgolo-Vicente, Karen Ritt, Mariana Rodrigues Pereira, PatrÃcia Maria Mendonça Torres, Roberto Paes-de-Carvalho, Elizabeth Giestal-de-Araujo,