Article ID Journal Published Year Pages File Type
10760337 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► We investigated mechanisms of mitochondrial regulation in rat hepatocytes. ► Tetradecylthioacetic acid (TTA) was employed to activate mitochondrial oxidation. ► Mitochondrial biogenesis and respiration were induced. ► It was confirmed that PPAR target genes were induced. ► The mechanism involved activation mTOR.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA)
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