| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760362 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠High level of folic acid led to PTEN, RARbeta2 and APC promoters hypermethylation. ⺠Folic acid caused DNA-mediated transcriptional silencing of PTEN, RARbeta2 and APC. ⺠MCF-7 cells are more susceptible for folic acid action than MDA-MB-231 cells. ⺠Effect of folic acid action depends on dose, timing and individual conditions.
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Authors
Katarzyna Lubecka-Pietruszewska, Agnieszka Kaufman-Szymczyk, Barbara Stefanska, Krystyna Fabianowska-Majewska,