Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760409 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠We generated mice lacking Atg5 and autophagy in keratin K5-positive epithelia. ⺠Suppression of autophagy in thymic epithelium was not associated with signs of autoimmunity. ⺠Autophagy was required for normal terminal differentiation of preputial gland cells. ⺠Autophagy-deficient cells of the preputial glands degraded nuclear DNA prematurely.
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Authors
Supawadee Sukseree, Heidemarie Rossiter, Michael Mildner, Johannes Pammer, Maria Buchberger, Florian Gruber, Ramida Watanapokasin, Erwin Tschachler, Leopold Eckhart,