Article ID Journal Published Year Pages File Type
10760425 Biochemical and Biophysical Research Communications 2013 5 Pages PDF
Abstract
► Effects of TFAM overexpression were examined at the individual level in Drosophila. ► Excess TFAM had a negative influence on lifespan under the standard condition. ► Overexpression of TFAM caused responsive reaction against strong oxidative stress. ► A possibility that TFAM is involved in the elimination of ROS is suggested.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Effects of overexpression of mitochondrial transcription factor A on lifespan and oxidative stress response in Drosophila melanogaster
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