Article ID Journal Published Year Pages File Type
10760476 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► ssDNA-dsRNA chimeras are cleaved in a position-specific manner in serum. ► The cleavage site is at the phosphodiester linkage between the first and second RNA. ► 2′ methoxylation of the first RNA prevents the cleavage. ► This activity of RNase may be related to siRNA defense system.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
ssDNA-dsRNAs are cleaved at the next to its chimera-junction point by an unknown RNase activity
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