Article ID Journal Published Year Pages File Type
10760484 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► Endogenous SIRT3 plays an essential role in mediating cell survival in cardiomyocytes. ► Overexpression of SIRT3 protects cells against oxidative stress-mediated cell death. ► The molecular mechanisms responsible for the protective effect of SIRT3 may involve the activity of the NF-κB pathway.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
SIRT3 protects cardiomyocytes from oxidative stress-mediated cell death by activating NF-κB
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