| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760485 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠The article revealed FoxP3 gene function in gastric cancer firstly. ⺠Present the novel roles of FoxP3 in inhibiting proliferation and promoting apoptosis in gastric cancer cells. ⺠Overexpression of FoxP3 increased proapoptotic molecules and repressed antiapoptotic molecules. ⺠Silencing of FoxP3 reduced the expression of proapoptotic genes, such as PARP, caspase-3 and caspase-9. ⺠FoxP3 is sufficient for activating the apoptotic signaling pathway.
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Authors
Gui-Fen Ma, Shi-Yao Chen, Zhi-Rong Sun, Qing Miao, Yi-Mei Liu, Xiao-Qing Zeng, Tian-Cheng Luo, Li-Li Ma, Jing-Jing Lian, Dong-Li Song,