Article ID Journal Published Year Pages File Type
10760492 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract
► MAPO1 stabilizes in the course of apoptosis triggered by O6-methylguanine. ► MAPO1 level is regulated by proteasome-dependent degradation pathway. ► Folliculin and AMPK stabilize MAPO1 in positive and negative manners, respectively. ► Folliculin retains an ability to stably bind to MAPO1 during apoptosis. ► AMPK dissociates gradually from MAPO1 during apoptosis.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Stabilization of MAPO1 by specific binding with folliculin and AMP-activated protein kinase in O6-methylguanine-induced apoptosis
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