| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760550 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠The renin activity of acidified prorenin (free form) depends on time and pH. ⺠Acidified prorenin at pH 4.5, 5.5, and 6.5 has similar binding affinity to (P)RR. ⺠Acidified prorenin at pH 3.3 hardly binds to (P)RR. ⺠(P)RR-bound acidified prorenin also shows the renin activity. ⺠Acidified prorenin could lead to pathogenesis of diseases by modulating RA system.
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Authors
A.H.M. Nurun Nabi, Kazal Boron Biswas, K.M. Nasrin Haque, Yoshie Arai, Tsutomu Nakagawa, Akio Ebihara, Atsuhiro Ichihara, Tadashi Inagami, Fumiaki Suzuki,