| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760593 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠A novel method to purify hydrophobic C-type lectin proteins (CLPs) was developed. ⺠The proteins were cloned, expressed and purified by sonication and wash steps. ⺠The purified CLPs had a yield 38 times higher than the traditional method. ⺠The CLPs from snake venom inhibited platelet aggregation with an IC50 of 100.57 μM. ⺠These snake protein types are useful in the development of novel drug therapies.
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Authors
Chunhui Yin, Ying Jia, Carlos A. Garcia,