| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760596 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠GRX1 overexpression protects myocardiac H9c2 cells against NO-induced apoptosis. ⺠NO-induced nuclear translocation of GAPDH is suppressed in GRX overexpressors. ⺠Oxidation of GAPDH by NO is less in GRX overexpressors than in controls.
Keywords
S-nitroso-N-acetyl-dl-penicillamineS-nitrosylationGSHGAPDHGRx3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromideAMSterminal deoxynucleotidyltransferase-mediated dUTP nick end labelingGSSGTrxMTTTUNELthioredoxinApoptosisSNAPCardiomyocyteNitric oxidereduced form of glutathioneoxidized glutathioneGlutaredoxinglyceraldehyde-3-phosphate dehydrogenase
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Authors
Chiaki Inadomi, Hiroaki Murata, Yoshito Ihara, Shinji Goto, Yoshishige Urata, Junji Yodoi, Takahito Kondo, Koji Sumikawa,