Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760626 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠Embryonic stem cells (ESCs) lacking non-canonical miRNAs proliferate slower. ⺠miR-320 and miR-702 are two non-canonical miRNAs expressed in ESCs. ⺠miR-320 and miR-702 promote proliferation of Dgcr8-deficient ESCs. ⺠miR-320 targets p57 and helps to release Dgcr8-deficient ESCs from G1 arrest. ⺠miR-702 targets p21 and helps to release Dgcr8-deficient ESCs from G1 arrest.
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Authors
Byeong-Moo Kim, Michael Y. Choi,