Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760631 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Melanoregulin-GFP targets extensively to the limiting membrane of the melanosome. ⺠Endogenous melanoregulin also targets extensively to the melanosome. ⺠Melanoregulin targeting to melanosomes and lysosomes requires N-terminal cysteines. ⺠SDM, metabolic labeling and inhibitors show that melanoregulin is palmitoylated on these cysteines. ⺠FRAP shows that melanoregulin is stably targeted to the melanosome membrane.
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Authors
Xufeng S. Wu, Jose A. Martina, John A. III,