| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760666 | Biochemical and Biophysical Research Communications | 2012 | 8 Pages |
Abstract
⺠EZH2 is overexpressed in the nuclei of renal cancer cells. ⺠Nuclear EZH2 is associated with advanced stage and worse survival of RCC patients. ⺠EZH2 is negatively regulated by miR-101 in renal cancer cells. ⺠Depletion of EZH2 leads to re-expression of p27Kip1. ⺠Reintroduction of miR-101 results in suppression of cell proliferation.
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Authors
Toshihiko Sakurai, Vladimir N. Bilim, Andrey V. Ugolkov, Kaori Yuuki, Masaaki Tsukigi, Teiichi Motoyama, Yoshihiko Tomita,